Cancer prevention and therapy by inhibiting soluble tumor necrosis factor
AssigneeUniversity of Pittsburgh—Of the Commonwealth System of Higher Education
InventorsNikola L. Vujanovic, Lazar Vujanovic
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Abstract
Methods are disclosed for inhibiting the development of a tumor in a subject. The methods include administering to a subject a therapeutically effective amount of a dominant negative tumor necrosis factor (DN-TNF)-α protein and/or a nucleic acid encoding the DN-TNF-α protein. The DN-TNF-α protein and/or a nucleic acid encoding the DN-TNF-α protein can be administered alone or in combination with other agents.
Claims31
A method for inhibiting the development of, or treating a tumor in a subject, comprising administering to a subject a therapeutically effective amount of a dominant negative tumor necrosis factor (DN-TNF)-α protein and/or a nucleic acid encoding the DN-TNF-α protein, thereby inhibiting the development of the tumor in a subject.
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Dependencies are inferred from the claim text.