A method of treatment
AssigneesHudson Institute of Medical Research, Monash University
InventorsEuan Wallace, Rebecca Lim
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Abstract
The present disclosure relates generally to the methods of treatment of mammalian subjects by an enhanced cell-based therapeutic approach in order to facilitate tissue and neuronal repair, regeneration and/or reparation. Medicaments useful in the treatment of mammalian subjects and methods of production of the medicaments are also encompassed by the present disclosure.
Claims22
A method of treating a mammalian subject, the method comprising systemic or local administration of mammalian amniotic exosomes derived from allogeneic mammalian amnion epithelial cells derived from a donor mammal of the same species as the mammalian subject.
A pharmaceutical composition comprising mammalian amniotic exosomes and one or more pharmaceutically acceptable carriers, excipients and/or diluents.
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An improved cell-based therapeutic method for treating a mammalian subject including a human subject by the use of amnion epithelial cells, the improvement comprising isolating amniotic exosomes from an immortalized amnion epithelial cell line and systemically or locally administrating to the subject in need of tissue or neuronal repair, regeneration and/or reparation.
Dependencies are inferred from the claim text.