Methods of treating retinal diseases
AssigneesAlimera Sciences, Inc., The Johns Hopkins University
InventorsKenneth E. Green, Peter Campochiaro, Yogita Kanan
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Abstract
A method of treating or inhibiting degeneration of a retina of a subject in need thereof comprising administering an effective amount of a compound of metipranolol, or a metabolite thereof, to an organ, a tissue, or the subject, wherein the degeneration of the retina is caused by an ocular disease. In some embodiments, the compound, or a metabolite thereof, is administered topically, orally, or parenterally. In some embodiments, a drug delivery vehicle comprising a dosage of the compound, or the metabolite of, is delivered parenterally via intravitreal injection. In further embodiments, the dosage may range from 0.5 μg/day-15 μg/day.
Claims29
A method of treating or inhibiting degeneration of a retina of a subject in need thereof comprising administering an effective amount of a compound of metipranolol, or a metabolite thereof, to an organ, a tissue, or the subject, wherein the degeneration of the retina is caused by an ocular disease selected from the group consisting of diabetic retinopathy, choroidal neovascularization, and retinitis pigmentosa.
A method of administering an effective amount of a compound of metipranolol, or a metabolite thereof, for treatment of an ocular condition affecting the health of a retina of a subject comprising injecting an effective amount of the metipranolol, or a metabolite thereof, into an organ, a tissue, or the subject, wherein the ocular condition is selected from the group consisting of diabetic retinopathy, choroidal neovascularization, and retinitis pigmentosa.
A method of treating or inhibiting dystrophy of rods and cones of a retina of a subject in need thereof comprising administering an effective amount of a compound of metipranolol, or a metabolite thereof, to an organ, a tissue, or the subject.
Dependencies are inferred from the claim text.