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US 2019/0336458 A1Published application
Eutectic formulations of cyclobenzaprine hydrochloride
AssigneeTonix Pharma Holdings Limited
InventorsSeth Lederman, Marino Nebuloni
Life of this patent
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Abstract
The present invention relates to pharmaceutical compositions and methods of manufacturing the same, comprising a eutectic of Cyclobenzaprine HCl and mannitol.
Claims25
1-28. (canceled)
A pharmaceutical composition comprising a eutectic of δ-mannitol and Cyclobenzaprine HCl, wherein the eutectic comprises 65%±2% Cyclobenzaprine HCl and 35%±2% δ-mannitol by weight.
A pharmaceutical composition comprising a eutectic of 65%±2% Cyclobenzaprine HCl and 35%±2% δ mannitol by weight, and a eutectic of 75%±2% Cyclobenzaprine HCl and 25%±2% β mannitol by weight.
Dependencies are inferred from the claim text.