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US 2019/0336451 A1Published application
Rifabutin-based compositions and methods for treating helicobacter pylori infection
AssigneeRedHill Biopharma Ltd.
InventorsReza Fathi, Gilead Raday, Guy Goldberg, Patrick Gosselin
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Abstract
Single oral solid dosage form comprising an immediate release first dosage composition having at least two antibiotic agents and a delayed release second dosage composition having a proton pump inhibitor are provided herein. The single oral solid dosage form according to some aspects of the invention can be used for the treatment of disorders associated with infection by H. pylori or the prevention of recurrence of disorders associated with infection by H. pylori.
Claims13
A capsule comprising a mixture of:
- immediate release dosage compositions having a size ranging from about 100 μm to about 2 mm, wherein each immediate release dosage composition comprises rifabutin and amoxicillin;
- and
- extended release dosage compositions having a size ranging from about 100 μm to about 2 mm, wherein each extended release dosage composition comprises a proton pump inhibitor.
Dependencies are inferred from the claim text.