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US 2019/0336449 A1Published application
Multiple unit dosage form comprising a core with individual core units covered by a mucoadhesive material and an enteric core coating
AssigneeTillotts Pharma AG
InventorsFelipe VARUM, Roberto BRAVO, Daniel PREISIG
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Abstract
The present invention relates to a multiple unit dosage form comprising a core, wherein the core comprises a plurality of individual units, each unit comprising a pharmaceutically active ingredient and each unit being covered with a mucoadhesive material, and wherein the multiple unit dosage form further comprises an enteric core coating layer. The invention furthermore relates to the use of said multiple unit dosage form in the treatment of inflammatory disorders, especially for the gastrointestinal tract.
Claims23
A multiple unit dosage form comprising:
- (a) a core comprised of a plurality of individual units, wherein each unit comprises:
- (a1) at least one pharmaceutically active ingredient, and each unit is covered by
- (a2) at least one mucoadhesive material, and
- (b) a core coating that completely covers the core and
- that includes at least one coating layer, namely an outer coating layer (b1), wherein the outer coating layer (b1) of the core coating (b) is an enteric coating layer that is substantially insoluble in the stomach of a patient and soluble in the intestine of a patient.
2 more elements
Dependencies are inferred from the claim text.