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US 2019/0336281 A1Published application
Heart valve mimicry
AssigneeJenaValve Technology, Inc.
InventorsPayam SAFFARI, Vicent Ming Hai CHOW, Makensley LORDEUS, Hussain S. RANGWALA, Gregory Edwin MIRIGIAN, John F. MIGLIAZZA, Victoria E. CARR-BRENDEL
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Abstract
The disclosure relates to a heart valve with improved functionality and durability.
Claims21
A replacement heart valve prosthesis comprising a stent component and a valve component, wherein:
- the valve component has a valve ratio of annulus to commissure distance (ACD) to annulus diameter (AD) of about 1.01 to 1.14;
- and
- the stent component comprises an inflow end region and an outflow end region each comprising a plurality of cells, wherein
- in the inflow end region,
- a ratio of area of a given cell to a neighboring cell is about 0.25 to 4,
- a ratio of height of a given cell to a neighboring cell is 0.5 to 2, or
- an aspect ratio of all cells of the inflow end region is about 1 to 2;
- and
- in the outflow end region,
- an aspect ratio of cells varies from about 1 to 3,
- cells vary in area in a single circumferential row, and the area of adjacent cells in circumferential rows varies from about 5 mm2 to 250 mm2, or
- heights of cells vary in a single circumferential row, and the height of adjacent cells in circumferential rows varies from about 3 mm to 30 mm.
9 more elements
The prosthesis according to claim 5,
- wherein the fastening portion comprises an arch.
(canceled)
A replacement heart valve prosthesis comprising a stent component and a valve component, wherein:
- the valve component has a valve ratio of annulus to commissure distance (ACD) to annulus diameter (AD) of about 1.01 to 1.14;
- and
- the stent component comprises
- an inflow end region and an outflow end region each comprising a plurality of cells, a number of cells per cm2 area being about 2 to 6 in the inflow end region and about 1 to 4 in the outflow end region;
- and
- at least one feature configured to engage with a native commissure of a native heart valve, the at least one feature being part of, or fixed to, a proximal end of the prosthesis.
3 more elements
Dependencies are inferred from the claim text.