Percutaneously-deployable intravascular embolic protection devices and methods
AssigneeMayo Foundation for Medical Education and Research
InventorsAtta Behfar, David L. Joyce, Mandeep Singh, Andre Terzic
Life of this patent
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Abstract
Embolic protection devices can be used to enhance the treatment of heart conditions such as, but not limited to, heart failure and aortic valve stenosis. For example, this document describes percutaneously-deployable intravascular embolic protection devices and methods for their use. The embolic protection devices can be used to capture and remove embolic materials that could otherwise cause adverse patient effects.
Claims15
An embolic protection device comprising:
- a cylindrical framework comprised of one or more elongate elements, the cylindrical framework being reconfigurable between a low-profile delivery configuration for containment within a delivery sheath and a diametrically-expanded configuration, the cylindrical framework being open at each end and defining an interior space;
- and
- a filter material disposed within the interior space, the filter material having a pore size that allows blood to pass through the filter material while capturing embolic materials within the filter material, the filter material defining an open passage configured for allowing passage of a catheter through the embolic protection device.
A method of implanting a trans-catheter aortic valve in a native aortic valve of a patient, the method comprising:
- navigating a first delivery sheath through the patient to position a distal end portion of the first delivery sheath in an ascending aorta of the patient;
- deploying an embolic protection device out from the first delivery sheath to engage with the ascending aorta, wherein the embolic protection device reconfigures from a low-profile delivery configuration to an expanded configuration upon emergence from the first delivery sheath, wherein the embolic protection device includes a filter material disposed within an interior space defined by a cylindrical framework of the embolic protection device, and wherein the filter material defines an open passage;
- while the embolic protection device is engaged with the ascending aorta, navigating a second delivery sheath through the patient and through the open passage to position a distal end portion of the second delivery sheath in the ascending aorta of the patient adjacent the native aortic valve;
- while the embolic protection device is engaged with the ascending aorta, deploying the trans-catheter aortic valve out from the second delivery sheath to engage with the native aortic valve;
- and
- removing the embolic protection device from the patient after the trans-catheter aortic valve is deployed.
A method of removing thrombus from a left ventricular assist device (LVAD) while the LVAD is implanted and operating within a patient, the method comprising:
- navigating a delivery sheath through the patient to position a distal end portion of the delivery sheath in an outflow conduit of the LVAD;
- deploying an embolic protection device out from the delivery sheath to engage with the outflow conduit, wherein the embolic protection device reconfigures from a low-profile delivery configuration to an expanded configuration upon emergence from the delivery sheath, wherein the embolic protection device includes a filter material disposed within an interior space defined by a cylindrical framework of the embolic protection device, and wherein the filter material defines an open passage;
- injecting a thrombolytic agent into a left ventricle of the patient such that the thrombolytic agent flows into the LVAD and causes detachment of thrombus from the LVAD;
- collecting at least some of the detached thrombus in the filter material;
- and
- removing the embolic protection device from the patient while the thrombus is in the filter material.
Dependencies are inferred from the claim text.