Determination of structure and traversal of occlusions using magnetic particles
AssigneePulse Therapeutics, Inc.
InventorsBrian L. Kidd, Sean C. Morris, Michael E. Sabo
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Abstract
This disclosure generally relates to systems and methods for facilitating determination of morphology (e.g., shape) and structure (e.g., size, rigidity) and/or penetrating channels (e.g., microchannels) of occlusions (e.g., clots, fluid obstructions, tumors, chronic total occlusions) involving magnetic particles (e.g., nanoparticles, microparticles) controlled by an external magnetic control system.
Claims20
A method of facilitating treatment of a therapeutic target within a body of a subject, the method comprising:
- delivering magnetic particles to a location near the therapeutic target within the body of the subject;
- applying a rotating magnetic field so as to cause the magnetic particles to agglomerate into stir bars and to generate a circulating motion adjacent the therapeutic target so as to cause at least some of the magnetic particles to be driven into an outer surface of the therapeutic target;
- and
- obtaining images indicative of a shape of the surface profile of the therapeutic target using an imaging modality capable of imaging the magnetic particles.
A method of facilitating treatment of a therapeutic target within a body of a subject, the method comprising:
- delivering magnetic particles to a location near the therapeutic target within the body of the subject;
- applying a rotating magnetic field so as to cause the magnetic particles to agglomerate into stir bars and to generate a circulating motion adjacent the therapeutic target so as to cause the magnetic particles to be driven within channels or voids present within the therapeutic target;
- and
- obtaining images indicative of the channels or voids present within the therapeutic target utilizing an imaging modality.
Dependencies are inferred from the claim text.