Pharmaceutical composition for preventing or treating breast cancer including crystalline polymorph of tetraarsenic hexoxide, and method for producing same
AssigneeChemas Co., Ltd.
InventorsIll Ju BAE, Zenglin LIAN
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Abstract
The present invention relates to a pharmaceutical composition for preventing or treating breast cancer which includes tetraarsenic hexoxide in which a crystalline polymorph a(As4O6-a), of tetraarsenic hexoxide is 99% or higher, and to a method for producing the same. The composition of the present invention exhibits excellent effects of inhibiting the proliferation and metastasis of cancer cells, and thus can be usefully used as an anticancer agent.
Claims5
A pharmaceutical composition containing tetraarsenic hexoxide (As4O6) as an active ingredient for prevention or treatment of breast cancer, wherein the tetraarsenic hexoxide includes 99 wt % or more of tetraarsenic hexoxide crystalline polymorph a having features (i) to (iii) below:
- (i) Cell parameters:
- a=b=c=11.0734 Å
- α=β=γ=90°
- V=1357.82 Å3
- (ii) As—O bond length:
- 1.786 Å
- (iii) O—As—O bond angle:
- 98.36°
A pharmaceutical composition containing tetraarsenic hexoxide (As4O6) as an active ingredient for inhibition of breast cancer metastasis, wherein the tetraarsenic hexoxide includes 99 wt % or more of tetraarsenic hexoxide crystalline polymorph a having features (i) to (iii) below:
- (i) Cell parameters:
- a=b=c=11.0734 Å
- α=β=γ=90°
- V=1357.82 Å3
- (ii) As—O bond length:
- 1.786 Å
- (iii) O—As—O bond angle:
- 98.36°
Dependencies are inferred from the claim text.