Devices and methods for generation and culture of 3d cell aggregates
AssigneeCorning Incorporated
InventorsYe Fang, Ann MeeJin Ferrie, Vasiliy Nikolaevich Goral, Gregory Roger Martin, Kaitlyn Mary Matias, Michael Kurt Schaefer, Allison Jean Tanner
Life of this patent
Estimating the term…
Abstract
The present disclosure relates to apparatuses, systems and methods for culturing cells. In particular, devices and methods are provided for generation and culture of 3d cell aggregates.
Claims23
A cell culture substrate comprising an array of microwells, each microwell comprising an opening into the microwell defined by a top well edge, corrugated microwell sidewalls, and a rounded well-bottom, wherein the corrugated microwell sidewalls are aligned to produce microwells in the gaps between the corrugated sidewalls.
2-7. (canceled)
10-11. (canceled)
15-21. (canceled)
A cell culture devices comprising a plurality of wells disposed therein;
- wherein the wells are arranged in at least one row;
- wherein the row is defined by two corrugated sidewalls aligned such that a gap between the sidewalls widens and narrows with each corrugation;
- wherein an upper portion of each well is defined by a widened gap between two narrowed gaps of the sidewalls.
Dependencies are inferred from the claim text.