Production of fatty acid derivatives
AssigneeReg Life Sciences, LLC
InventorAlfred GAERTNER
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Abstract
Methods and compositions for producing fatty acid derivatives, for example, fatty esters, and commercial fuel compositions comprising fatty acid derivatives are described.
Claims51
A method of producing a fatty acid derivative, the method comprising culturing a host cell in the presence of a carbon source, wherein the host cell is genetically engineered to express or overexpress a gene encoding an ester synthase, and isolating the fatty acid derivative.
A genetically engineered microorganism comprising at least one gene encoding an ester synthase, wherein the gene encoding the ester synthase is overexpressed relative to a wild type ester synthase, and wherein the microorganism produces an increased level of a fatty ester relative to a wild-type microorganism.
A genetically engineered microorganism comprising an exogenous control sequence stably incorporated into the genomic DNA of the microorganism upstream of a gene encoding an ester synthase, wherein the microorganism produces an increased level of a fatty ester relative to a wild-type microorganism.
Dependencies are inferred from the claim text.