Production of frambinone by a recombinant fungal microorganism
AssigneeLesaffre Et Compagnie
InventorsAlexander Matthias Farwick, Thomas Desfougeres, Georges Pignede, Anaïs Roussel, Isabelle Mouly, Brieuc Morvan
Life of this patent
Estimating the term…
Abstract
The invention relates to a genetically modified fungal microorganism for the production of frambinone, said microorganism having the following characteristics: —the capacity to produce frambinone from tyrosine; and —a limited capacity or no capacity to break tyrosine down into tyrosol, p-hydroxyphenylacetaldehyde and/or p-hydroxyphenylacetate; and to the use of same for producing frambinone.
Claims19
A genetically modified fungal microorganism for the production of frambinone, said microorganism having the following characteristics:
- a capacity to produce frambinone from tyrosine;
- and
- a limited capacity or no capacity to break tyrosine down into tyrosol, p-hydroxyphenylacetaldehyde and/or p-hydroxyphenylacetate.
(canceled)
A process for the production of frambinone comprising culturing a fungal microorganism with a capacity to produce frambinone from tyrosine in a medium comprising tyrosine and a repressor of the path for breaking tyrosine down into tyrosol, p-hydroxyphenylacetaldehyde and/or p-hydroxyphenylacetate.
Dependencies are inferred from the claim text.