Determination method and system thereof

A determination system, comprising:

• a sample reservoir configured to receive a urine sample, wherein the urine sample comprises a first urine sample and a second urine sample;
• a diluent reservoir configured to store a diluent;
• a mixing reservoir configured for receiving and mixing the diluent and the second urine sample to form a first diluted urine sample and a second diluted urine sample;
• a creatinine detection reservoir connected to the mixing reservoir, wherein the creatinine detection reservoir is for receiving the first diluted urine sample;
• an albumin detection reservoir connected to the mixing reservoir, and is for receiving the second diluted urine sample, wherein the mixing reservoir is connected with the sample reservoir, the diluent reservoir, the creatinine detection reservoir, and the albumin detection reservoir, and the mixing reservoir is configured to mix the second urine sample from the sample reservoir with the diluent and then introduce a mixture of the second urine sample and the diluent to the creatinine detection reservoir and the albumin detection reservoir;
• a total protein detection reservoir connected to the sample reservoir, wherein the total protein detection reservoir is for receiving the first urine sample;
• a detection device configured to measure a total protein concentration of the first urine sample, a creatinine concentration of the first diluted urine sample and an albumin concentration of the second diluted urine sample;
• and
• a processor configured to process the total protein concentration, the creatinine concentration, and the albumin concentration to calculate a urine protein to creatinine ratio (UPCR) and a urine albumin to creatinine ratio (UACR), wherein the UPCR is defined as the ratio of the total protein concentration to the creatinine concentration, while the UACR is defined as the ratio of the albumin concentration to the creatinine concentration.