Method for identification, selection and analysis of tumour cells
AssigneeMenarini Silicon Biosystems S.p.A.
InventorsNicolò Manaresi, Gianni Medoro, Giuseppe Giorgini
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Abstract
The present invention relates to a method for the diagnosis of tumoural conditions and/or of the corresponding state of advance, wherein a sample from a patient comprising at least one tumour cell is obtained. According to the invention, a purified specimen of the at least one tumour cell is obtained by individually selecting and isolating single cells in a microfluidic device the purified specimen having a purity of at least 90%. On the purified specimen thus obtained there is subsequently performed a molecular analysis such as to highlight a characteristic thereof suited to enabling diagnosis.
Claims36
A method for the diagnosis of tumoural conditions and/or of the corresponding state of advance, comprising the steps of:
- a. obtaining a sample from a patient, the sample comprising at least one tumour cell or portion thereof;
- b. obtaining a purified specimen of said a least one tumour cell or portion thereof by individually selecting and isolating single cells or portions thereof in a microfluidic device wherein the at least one tumor cell or portion thereof is suspended in a fluid, the purified specimen having a purity of at least 90%;
- c. performing a molecular analysis on said purified specimen to highlight at least one characteristic of said at least one tumour cell suited to enabling said diagnosis.
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Dependencies are inferred from the claim text.