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US 2019/0292526 A1Published application
Pyruvate dehydrogenase variants, a microorganism comprising the same and a method for producing l-amino acid using the same
AssigneeCj Cheiljedang Corporation
InventorsLan Huh, Jun Ok Moon, Hyun Won Bae, Hyung Joon Kim, Sung Ki Song
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Abstract
The present disclosure relates to a novel pyruvate dehydrogenase variant, a polynucleotide encoding the pyruvate dehydrogenase variant, a microorganism of the genus Corynebacterium producing L-amino acid, which includes the pyruvate dehydrogenase variant, and a method for producing an L-amino acid using the microorganism.
Claims10
1-14. (canceled)
A polypeptide having pyruvate dehydrogenase activity, wherein the polypeptide comprises an amino acid sequence having at least a 95% sequence identity to the SEQ ID NO:
- 1 and comprising at least one amino acid substitutions in a region of amino acids at positions from 190 to 205 of SEQ ID NO:1.
Dependencies are inferred from the claim text.