Cell delivery system and methods of operation thereof
AssigneeSanBio, Inc.
InventorMichael McGROGAN
Life of this patent
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Abstract
A method of preparing a syringe in connection with a therapeutic treatment is disclosed. The method can include removing a plunger of the syringe from a barrel of the syringe, aligning the barrel in a horizontal orientation, filling a lumen of the barrel with a viscous material through an opening at a proximal end of the barrel, and inserting a plunger tip into the lumen to seal the lumen. The method can also include attaching an implantation device to a hub coupled to the barrel at a distal end of the barrel. The method can also include depressing the plunger until the cell suspension fills the implantation device and a droplet of the cell suspension is expelled from a distal tip of the implantation device.
Claims33
A method of preparing a syringe in connection with a therapeutic treatment, the method comprising:
- removing a plunger of the syringe from a barrel of the syringe, wherein the barrel has a proximal end, a distal end, and a lumen in between the proximal end and the distal end;
- aligning the barrel in a horizontal orientation;
- filling at least part of the lumen with a viscous material through an opening at the proximal end;
- inserting a plunger tip of the plunger into the lumen to seal the lumen;
- attaching an implantation device to a hub of the syringe, wherein the hub is coupled to the barrel at the distal end;
- and
- depressing the plunger until the viscous material fills the implantation device and a droplet of the viscous material is expelled from the implantation device through a distal tip of the implantation device.
A method of implanting a viscous material into a subject in connection with a therapeutic treatment, the method comprising:
- removing a plunger of a syringe from a barrel of the syringe, wherein the barrel has a proximal end, a distal end, and a lumen in between the proximal end and the distal end;
- filling at least part of the lumen with the viscous material through an opening at the proximal end and reinserting the plunger;
- coupling a needle or a cannula to the distal end of the barrel of the syringe;
- injecting the viscous material into the subject using the syringe at one or more deposit sites;
- and
- rotating the syringe about a longitudinal axis of the syringe after each injection.
A method of treating a subject with cells, the method comprising:
- removing a plunger of a syringe from a barrel of the syringe, wherein the barrel has a proximal end, a distal end, and a lumen in between the proximal end and the distal end;
- filling at least part of the lumen with the cells through an opening at the proximal end and reinserting the plunger;
- coupling an implantation device to the syringe at the distal end of the barrel;
- injecting an amount of the cells into the subject using the syringe and the implantation device at a first deposit site in the subject;
- rotating at least one of the syringe and the implantation device about a longitudinal axis;
- and
- injecting another amount of the cells into the subject using the syringe and the implantation device at a second deposit site in the subject.
Dependencies are inferred from the claim text.