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US 2019/0290831 A1Published application
Biological component collection system and flow path internal pressure acquisition method
AssigneeTerumo Kabushiki Kaisha
InventorMasatsugu IGARASHI
Life of this patent
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Abstract
A blood component collection system (10) includes a first internal pressure calculation unit (110) adapted to calculate a first internal pressure of a first pressed portion (60) using first calibration curve data (118), a second internal pressure calculation unit (112) adapted to calculate a second internal pressure of a second pressed portion (62) using second calibration curve data (120), and a correction unit (114) adapted to correct the first calibration curve data (118) in a manner so that, during a blood returning operation, the first internal pressure calculated by the first internal pressure calculation unit (110) becomes equal to the second internal pressure calculated by the second internal pressure calculation unit (112).
Claims10
A biological component collection system comprising
- a separation device adapted to separate a biological component from a biological liquid, and having
- a first load detecting unit,
- a second load detecting unit,
- at least one pump, and
- a biological component collection device configured to collect a desired biological component in the biological liquid, be attachable to the separation device, and in which a collection line and a returning line are formed,
- the biological component collection system further comprising means for performing a plurality of times a cycle including a collection operation in which the biological liquid is allowed to flow from a donor through the collection line to the separation device under an action of the collection and returning pump, and a returning operation for returning remaining biological components to the donor from the separation device through the returning line under the action of the collection and returning pump;
- wherein the biological component collection device is formed of a soft, flexible material, and has a first line forming member and a second line forming member defining the collection line and the returning line that are formed by wall portions;
- in the first line forming member, there is provided a first applied load measurement unit adapted to measure a load applied to the wall portion of the first line forming member by the first load detecting unit, in a device mounted state in which the biological component collection device is mounted in the separation device;
- in the second line forming member, there is provided a second applied load measurement unit adapted to measure a load applied to the wall portion of the second line forming member by the second load detecting unit in the device mounted state;
- and
- respective inner holes of the collection line and the returning line are in communication with each other at a time of the returning operation;
- the separation device comprising:
- a first internal pressure calculation unit adapted to calculate a first internal pressure of the first applied load measurement unit on the basis of a first detection signal from the first load detecting unit and first internal pressure calculation data;
- a second internal pressure calculation unit adapted to calculate a second internal pressure of the second applied load measurement unit on the basis of a second detection signal from the second load detecting unit and second internal pressure calculation data;
- and
- a calibration unit adapted to correct the first internal pressure calculation data in a manner so that, during the returning operation, the first internal pressure calculated by the first internal pressure calculation unit becomes equal to the second internal pressure calculated by the second internal pressure calculation unit.
13 more elements
A biological component collection system equipped with
- a separation device having a first load detecting unit and a second load detecting unit and which is adapted to separate a biological component from a biological liquid,
- a biological component collection device configured to collect a desired biological component in the biological liquid and be attachable to the separation device and in which a collection line and a returning line are formed, and a collection and returning pump, the biological component collection system performing a plurality of times a cycle including
- a collection operation in which the biological liquid is allowed to flow from a donor through the collection line to the separation device under an action of the collection and returning pump, and
- a returning operation for returning remaining biological components to the donor from the separation device through the returning line under the action of the collection and returning pump;
- wherein, in the biological component collection device, there are formed:
- a first coupling member adapted to couple the collection line and the returning line to each other;
- and
- a second coupling member which is positioned more on a side of the separation device than the first coupling member, and which is adapted to couple the collection line and the returning line to each other on the side of the separation device;
- the separation device comprising:
- a first clamp adapted to close and open the collection line;
- and
- a second clamp adapted to close and open the returning line;
- wherein, when the returning operation is started, and after the first clamp has opened the collection line for a predetermined time period together with the second clamp having opened the returning line, the first clamp closes the collection line.
10 more elements
A flow path internal pressure acquisition method in which there is used a biological component collection system equipped with
- a separation device having a first load detecting unit and a second load detecting unit and which is adapted to separate a biological component from a biological liquid, and having at least one pump;
- and
- a biological component collection device configured to be attachable to the separation device and in which a collection line and a returning line are formed, the internal pressure acquisition method comprising
- performing a plurality of times a cycle including
- collecting the biological liquid from a donor through the collection line to the separation device, and
- returning remaining biological components to the donor from the separation device through the returning line;
- measuring a first load applied to a first wall portion of said collection device by the first load detecting unit;
- measuring a second load applied to a second wall portion of said collection device by the second load detecting unit;
- and
- the flow path internal pressure acquisition method comprising:
- a returning determination step of determining whether or not it is during a collection operation;
- and
- a calibration step of performing calibration of first internal pressure calculation data, for a case in which, in the returning determination step, it is determined that it is during the returning operation;
- and in the calibration step, there are performed:
- a first internal pressure calculation step of calculating a first internal pressure of the first applied load measurement unit on the basis of a first detection signal from the first load detecting unit and the first internal pressure calculation data;
- a second internal pressure calculation step of calculating a second internal pressure of the second applied load measurement unit on the basis of a second detection signal from the second load detecting unit and second internal pressure calculation data;
- and
- a slope correcting step of correcting the first internal pressure calculation data in a manner so that the first internal pressure calculated by the first internal pressure calculation step becomes equal to the second internal pressure calculated by the second internal pressure calculation step.
15 more elements
Dependencies are inferred from the claim text.