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AssigneesCentro Cardiologico Monzino S.P.A., The University Court of the University of Edinburgh
InventorsMaurizio PESCE, Rosaria SANTORO, Mark BRADLEY, Seshasailam VENKATESWARAN
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The present invention relates to a polymer having a first monomer selected from the group consisting of: styrene, MMA, HEMA or MEMA and a second monomer selected from the group consisting of: GMA, DEAEA, DEAEMA, DMAA, BAEMA, 4-vinylpyridine, DMVBA, 1-vinylimidazole, DMAEA or a combination thereof as coating agent for a scaffold or a medical device, to promote cellular adhesion and/or cell growth or for the manufacture of yarns or threads. The polymer may further contain a third monomer selected from the group consisting of: BMA, DEGMEMA, DAAA and MMA. The invention also relates to a scaffold, a medical device, a yarn, a thread or a textile coated or manufactured with the polymers of the invention and relative methods.
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The scaffold or a medical device of claim 18 wherein the polymer further comprises a third monomer selected from the group consisting of:
The scaffold or a medical device of claim 18 wherein the polymer comprises monomers selected from the group consisting of:
The scaffold or a medical device of claim 18 wherein the ratio between the first monomer and the second monomer is between 40:60 and 90:10.
The scaffold or a medical device of claim 18 wherein the polymer is functionalized.
The scaffold or a medical device of claim 18 wherein the polymer is PA6, PA98, PA309, PA316, PA317, PA321, PA338, PA426, PA438 (Ranked with a score 3 according to screening results), PA104, PA111, PA112, PA134, PA167, PA176, PA181, PA187, PA255, PA285, PA295, PA296, PA318, PA319, PA324, PA326, PA329, PA354, PA364, PA506, PA512, PA516, PA531 (Ranked with a score 2 according to screening results) as defined in Table I.
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The scaffold or a medical device of claim 18, wherein the medical device is implantable or the scaffold is bio-absorbable.
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A scaffold or a medical device coated with or comprising a polymer comprising:
A yarn or a thread manufactured with a polymer comprising:
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A method to coat a scaffold or a medical device with a polymer comprising:
A 3-D printed scaffold manufactured with a polymer comprising:
Dependencies are inferred from the claim text.