Compositions and methods for the treatment of cancer
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Abstract
This disclosure provides compositions and methods for treating cancer or inducing an immune response to the cancer in a subject by administering to the subject an effective amount of an isoaspartylated protein or a fragment thereof or an antibody that binds specifically to an isoaspartylated protein or a fragment thereof. In another aspect, the disclosure also provides a pharmaceutical composition, comprising, consisting essentially of, or yet further consisting of an effective amount of the isoaspartylated protein or a fragment thereof or antibody that binds specifically to an isoaspartylated protein or a fragment thereof; and a pharmaceutically acceptable carrier.
Claims23
A method of treating a cancer or inducing an immune response in a subject suffering from a cancer, comprising administering to the subject an effective amount of an isoaspartylated protein or a fragment thereof, or an antibody or antigen binding fragment that binds specifically to an isoaspartylated protein or a fragment thereof.
(canceled)
A composition, comprising:
- a. an isoaspartylated protein or a fragment thereof, or an equivalent of each thereof, or
- b. an antibody that binds specifically to an isoaspartylated protein or a fragment thereof;
- and optionally a carrier.
-23. (canceled)
-28. (canceled)
Dependencies are inferred from the claim text.