Conjugates of an il-7 moiety and a polymer
AssigneeNektar Therapeutics
InventorsDeborah H. Charych, Ping Zhang, Peter Benedict Kirk
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Abstract
Conjugates of an IL-7 moiety and one or more nonpeptidic, water-soluble polymers are provided. Typically, the non-peptidic, water-soluble polymer is poly(ethylene glycol) or a derivative thereof. Also provided, among other things, are compositions comprising conjugates, methods of making conjugates, and methods of administering compositions to an individual.
Claims20
A conjugate comprising an interleukin-7 (IL-7) moiety covalently attached to a water-soluble polymer.
(canceled)
A method for making an interleukin-7 water-soluble polymer conjugate, the method comprising comprising contacting, under conjugation conditions, an interleukin-7 (IL-7) moiety with a water-soluble polymeric reagent comprising a reactive group suitable for reaction with one or more functional groups of the Interleukin-7 moiety.
Dependencies are inferred from the claim text.