Probiotic composition for preventing, improving or alleviating pancreatic cancer and application thereof

A probiotic composition for preventing, improving or alleviating the pancreatic cancer, comprising:

• Lactobacillus paracasei GMNL-133, wherein the Lactobacillus paracasei GMNL-133 is deposited with an accession number of CCTCC M 2011331 in China Center for Type Culture Collection (CCTCC), Wuhan University, Wuhan 430072, People's Republic of China, on Sep. 26, 2011;
• and
• Lactobacillus reuteri GMNL-89, wherein the Lactobacillus reuteri GMNL-89 was deposited with an accession number of CCTCC M 207154 in China Center for Type Culture Collection (CCTCC), Wuhan University, Wuhan 430072, People's Republic of China, on Nov. 19, 2007, and
• wherein a ratio of the Lactobacillus paracasei GMNL-133 to the Lactobacillus reuteri GMNL-89 in bacterial cell numbers is 2:1 to 1:2.