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US 2019/0290681 A1Published application
Compositions, systems, kits, and methods for treating an infection
AssigneeNovan, Inc.
InventorsRyan DOXEY, Nathan STASKO, Megan MARTIN
Life of this patent
Estimating the term…
Abstract
Provided herein are compositions, systems, kits, and methods for treating a viral, bacterial, protozoan, and/or fungal (e.g., onychomycosis and/or tinea pedis) infection.
Claims29
A composition comprising:
- a viscosity increasing agent present in an amount of about 0.1% to about 10% by weight of the composition,
- an emollient present in an amount of about 1% to about 30% by weight of the composition,
- a humectant present in an amount of about 1% to about 30% by weight of the composition,
- a solvent present in an amount of about 1% to about 20% by weight of the composition, and
- a co-solvent present in an amount of about 1% to about 50% by weight of the composition.
2 more elements
5-6. (canceled)
9-10. (canceled)
(canceled)
A composition comprising:
- a thickening agent present in an amount of about 0.1% to about 25% by weight of the composition,
- water present in an amount of about 50% to about 99% by weight of the composition, and
- a buffering agent present in an amount of about 0.01% to about 20% by weight of the composition.
21-34. (canceled)
36-42. (canceled)
44-51. (canceled)
53-62. (canceled)
64-66. (canceled)
A method of treating and/or preventing a viral, bacterial, protozoan, and/or fungal infection in and/or on a subject, the method comprising:
- administering a composition comprising a nitric oxide (NO)-releasing macromolecule to the subject, wherein the composition delivers a total amount of NO of at least about 50 or 100 nmol of NO/mg of the composition at about 1, 3, 5, 10, 20, 30, 40, 50, or 60 minute(s) after an initial time point as measured by in vitro release as measured by in vitro release, thereby treating and/or preventing the viral, bacterial, protozoan, and/or fungal infection in and/or on the subject.
68-77. (canceled)
Dependencies are inferred from the claim text.