Back to results
US 2019/0290628 A1Published application
N3,n6-bis(2-(5-methoxy-1h-indole-3-yl)ethyl)-2,6-dimethyl-4-(2-nitrophenyl)pyridine-3,5-dicarboxamide and use thereof in the field of neurotoxicity
AssigneeAtatüRk üNiversitesi Bilimsel Arastirma Projeleri Birimi
InventorsAhmet Hacimuftuoglu, Orhan Ates, Nurullah Saracoglu, Ali Taghizadehghalehjoughi, Farrokh Lafzi
Life of this patent
Estimating the term…
Abstract
The invention relates to a molecule enabling removal of neurotoxicity observed in neuron cells due to various reasons.
Claims5
A method for production of N3,N5-bis(2-(5-methoxy-1H-indole-3-yl)ethyl)-2,6-dimethyl-4-(2-nitrophenyl)pyridine-3,5-dicarboxamide molecule with the below given formulation:
- which eliminates neurotoxicity observed in neuron cells;
- characterized in comprising the operation steps of:
- a) synthesis of 5-methoxytryptamine,
- b) synthesis of dimethyl 2,6-dimethyl-4-(2-nitrophenyl)pyridine-3,5-dicarboxylate,
- c) synthesis of 2,6-dimethyl-4-(2-nitrophenyl)pyridine-3,5-dicarboxylic acid,
- d)
- dissolving the synthesized 2,6-dimethyl-4-(2-nitrophenyl)pyridine-3,5-dicarboxylic acid in THF, and stirring following addition of HOBt,
- obtaining the 1st mixture after addition of DCC to the resulting mixture and stirring,
- in another reaction vessel, dissolving the synthesized 5-methoxytryptamine in THF and then obtaining the 2nd mixture following addition of Et3N and mixing,
- e) adding the resulting 2nd mixture to the 1st mixture and stirring.
7 more elements
Dependencies are inferred from the claim text.