Anti-malarial pharmaceutical composition
AssigneeProtopharma Limited
InventorsClive Booles, Calvin Ross, Martin Sams
Life of this patent
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Abstract
The invention provides pharmaceutical compositions for the treatment and prophylaxis of malaria, comprising artemether and a medium chain triglyceride formulated for transmucosal sublingual, buccal or nasal delivery, especially by a spray. Also provided are delivery devices containing the compositions.
Claims18
A pharmaceutical composition comprising:
- artemether or arteether;
- and a pharmaceutically-acceptable excipient selected from the group consisting of:
- a medium chain length triglyceride;
- a short chain triglyceride;
- an omega-3-marine triglyceride;
- and a fish oil, rich in omega-3-acids;
- said composition formulated for transmucosal sublingual, buccal, or nasal dosage.
A kit for the treatment or prophylaxis of malaria comprising a pharmaceutical composition comprising:
- artemether or arteether;
- and
- a pharmaceutically-acceptable excipient selected from the group consisting of:
- a medium chain length triglyceride;
- a short chain triglyceride;
- an omega-3-marine triglyceride;
- and a fish oil, rich in omega-3-acids;
- said composition formulated for transmucosal sublingual, buccal, or nasal dosage;
- and
- instructions to administer said pharmaceutical composition to a patient in need thereof by the transmucosal sublingual, buccal, or nasal route.
A method of treating a disease responsive to artemether or arteether, comprising the administration to a patient in need thereof of a therapeutically effective amount of artemether or arteether by the transmucosal sublingual, buccal, or nasal route.
Dependencies are inferred from the claim text.