System and methods for wireless drug delivery on command

A method for fabricating a miniaturized implantable device:

• fabricating an electronic system by monolithically integrating the electronic system on a first face of a substrate, the electronic system comprising an energy storage element adapted to be charged through a wireless communication link;
• fabricating a coil by monolithically integrating the coil on the first face of the substrate, the coil being configured to provide the wireless communication link;
• and
• fixating at least one hermetic package, containing a liquid payload, on the first surface of the substrate, a portion of the hermetic package being positioned above the coil,
• wherein the energy storage element is configured to provide energy to rupture a seal of the hermetic package, thereby dispensing the liquid payload.