Apparatus and methods for determining pulse wave velocity using multiple pressure sensors
AssigneeKoninklijke Philips N.V.
InventorsCharles Frederik SIO, Arjen VAN DER HORST, Maarten Petrus Joseph KUENEN
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Abstract
Devices, systems and methods for pulse wave velocity determination in a renal artery are disclosed. An intravascular system may be included with two or more sensors disposed a certain distance apart on a flexible, elongate member. The sensors may be configured to receive pressure measurements associated with pulse waves moving through the renal artery, at different times. This difference in time and the distance between the 5 sensors may be used to calculate pulse wave velocity.
Claims17
An apparatus for pulse wave velocity (PWV) determination in a vessel, the apparatus comprising:
- an intravascular device configured to be positioned within the vessel, the intravascular device including:
- a flexible elongate member having a proximal portion and a distal portion;
- a first pressure sensor coupled to the distal portion of the flexible elongate member;
- and
- a second pressure sensor coupled to the distal portion of the flexible elongate member at a position spaced from the first pressure sensor by a first distance along a length of the flexible elongate member such that the first pressure sensor is configured to monitor pressure within the vessel at a first location and the second pressure sensor is configured to monitor pressure within the vessel at a second location spaced from the first location;
- and
- a processing system in communication with the intravascular device, the processing system configured to:
- receive first pressure data associated with the monitoring of the pressure at the first location within the vessel by the first pressure sensor;
- receive second pressure data associated with the monitoring of the pressure at the second location within the vessel by the second pressure sensor;
- and
- determine a pulse wave velocity of fluid within the vessel based on the received first and second pressure data,
- wherein the vessel is a renal artery and the sampling frequency of the first and the second pressure sensor is 10 kHz or higher, more preferably, 20 kHz or higher, most preferably, 40 kHz or higher.
A method of determining pulse wave velocity (PWV) in a vessel, comprising:
- monitoring a pressure at a first location within the vessel with a first pressure sensor;
- monitoring a pressure at a second location within the vessel with a second pressure sensor, wherein the second location is spaced from the first location along a length of the vessel by a first distance;
- receiving first pressure data associated with the monitoring of the pressure at the first location within the vessel by the first pressure sensor;
- receiving second pressure data associated with the monitoring of the pressure at the second location within the vessel by the second pressure sensor;
- and
- determining a pulse wave velocity of fluid within the vessel based on the received first and second pressure data,
- wherein the vessel is a renal artery and the sampling frequency of the first and the second pressure sensor is 10 kHz or higher, more preferably, 20 kHz or higher, most preferably, 40 kHz or higher.
Dependencies are inferred from the claim text.