Sugar compositions for tableting by direct compression
AssigneeRoquette Freres
InventorLiuming ZHOU
Life of this patent
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Abstract
Directly compressible compositions that include more than 30% by weight of allulose, and tablets obtainable thereof.
Claims19
A directly compressible composition comprising allulose as a direct compression excipient.
Allulose which is compressible in the sole presence of a lubricant, to form a tablet having a diameter of 13 mm, a weight of 800+/−5 mg, a cylindrical shape with convex faces with a radius of curvature of 13 mm, whose hardness is greater than 50 N at at least one compression force ranging from 5 to 20 kN, the ejection force being lower than 1200 N.
A directly compressible composition comprising allulose, wherein said allulose represents at least 30% of said directly compressible composition, said percentage being expressed in dry weight with respect to the total dry weight of said directly compressible composition.
A tablet comprising allulose, wherein allulose represents at least 30% of said tablet, said percentage being expressed in dry weight with respect to the total dry weight of said tablet.
A process for the manufacture of allulose, comprising:
- a step (a) of providing allulose obtained by crystallization in water or in a mixture of ethanol and water;
- a step (b) of grinding allulose obtained in step (a);
- a step (c) of sieving the allulose obtained in step (b), so as to obtain allulose having mean volume diameter D 4,3 greater than 45 μm and equal to or lower than 310 μm;
- a step (d) of recovering the allulose obtained in step (c).
Dependencies are inferred from the claim text.