Back to results
US 2019/0270768 A1Published application
Process for the synthesis of amide bonds with the aid of novel catalysts
AssigneeMerck Patent GmbH
InventorsNikolai (Mykola) IGNATYEV, Walter FRANK, Peter BARTHEN, Myroslav VYSOTSKY
Life of this patent
Estimating the term…
Abstract
The invention relates to a process for the production of amide bonds, in particular peptide bonds, with the aid of novel amide linking reagents containing an anion of the formula (I), to the novel reagents, and to the preparation thereof.
Claims7
Process for the production of an amide bond by reaction of an acid with a primary or secondary amine in the presence of a base with the aid of an amide linking reagent, characterised in that use is made of at least one amide linking reagent containing an anion of the formula (I),
- [P(CnF2n+1)yF6-y]− (I),
- where
- n stands on each occurrence, independently, for 1, 2, 3, 4, 5, 6, 7 or 8 and
- y stands for 1, 2, 3 or 4.
1 more element
Dependencies are inferred from the claim text.