Detecting an analyte
AssigneeThe University of Queensland
InventorChengzhong YU
Life of this patent
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Abstract
Provided herein is a method for detecting an analyte in a sample, which includes contacting the analyte with a nanoparticle having a core, a pore extending radially from said core, a binding agent for binding the analyte and a detection agent immobilized within the pore. A kit including such a nanoparticle and a method of generating a nanoparticle displaying an anchoring group is also provided. In addition, provided herein is a composition including a nanoparticle having a core and a radially extending pore having quantum dots immobilized therein that is dispersed in and/or on a substrate. Also provided are products, such as a display device, a LED device and a solar cell, that include the composition as well as methods of using and making said composition.
Claims30
A method for detecting an analyte in a sample, including the step of contacting said analyte with a nanoparticle to facilitate binding thereto, wherein the nanoparticle comprises:
- (i) a core;
- (ii) a pore extending radially from said core;
- (iii) a binding agent for binding the analyte;
- and
- (iv) a detection agent immobilized within said pore;
- to thereby detect said analyte
A diagnostic kit comprising:
- (a) a nanoparticle for detecting an analyte, wherein the nanoparticle comprises:
- (i) a core;
- (ii) a pore extending radially from said core;
- (iii) a binding agent for binding the analyte;
- and
- (iv) a detection agent immobilized within said pore;
- and
- (b) instructions for use.
(canceled)
8-11. (canceled)
13-14. (canceled)
A method for generating a nanoparticle displaying an anchoring group including the steps of:
- (i) providing a metal or metalloid source;
- (ii) contacting the metal or metalloid source with a base and optionally a surfactant in a liquid environment;
- (iii) contacting the product of step (ii) with a compound displaying the anchoring group;
- to thereby generate the nanoparticle displaying an anchoring group.
17-19. (canceled)
A composition comprising a nanoparticle dispersed in and/or on a substrate, wherein the nanoparticle comprises:
- (i) a core;
- (ii) a pore extending radially from said core;
- and
- (iii) a plurality of quantum dots immobilized within said pore.
(canceled)
26-31. (canceled)
33-35. (canceled)
(canceled)
(canceled)
A method for generating a nanoparticle having a plurality of quantum dots immobilized thereon including the steps of:
- providing a metal or metalloid source;
- (ii) contacting the metal or metalloid source with a base and optionally a surfactant in a liquid environment;
- (iii) contacting the product of step (ii) with a compound displaying the anchoring group;
- (iv) contacting the product of step (iii) with said quantum dots;
- to thereby generate the nanoparticle having the plurality of quantum dots immobilized thereon.
43-46. (canceled)
Dependencies are inferred from the claim text.