Back to results
US 2019/0262497 A1Published application
Therapeutic Acrylates as Enhanced Medical Adhesives
AssigneeCarnegie Mellon University
InventorsStefanie A. Sydlik, Zoe Wright
Life of this patent
Estimating the term…
Abstract
Provided herein are therapeutic acrylate compounds useful as medical adhesives, comprising a therapeutic agent covalently linked to a methacrylate or cyanoacrylate moiety. Adhesive compositions and kits, such as liquid sutures and bone cement also are provided along with uses for the compositions.
Claims25
An acrylate compound comprising one or more acrylate moieties covalently linked to a therapeutic agent moiety by an anhydride bond, a thioester bond, an ester bond, or an amide bond.
-15. (canceled)
(canceled)
A kit for preparation of a bone cement, comprising:
- a first vessel containing an acrylate polymer powder;
- and
- a second vessel comprising a liquid acrylate adhesive,
- wherein either the acrylate polymer powder comprises a residue of a therapeutic acrylate monomer, or the liquid acrylate adhesive comprises a therapeutic acrylate monomer, and wherein the therapeutic acrylate monomer has the structure
- where R is an anhydride bond, a thioester bond, an ester bond, or an amide bond, R1 is a therapeutic agent moiety, and R2 is a cyano or methyl group.
2 more elements
(canceled)
Dependencies are inferred from the claim text.