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US 2019/0241647 A1Published application
Compositions And Methods For Treating Angiogenesis-Related Disorders
AssigneeFFE Therapeutics LLC
InventorVictor Gurewich
Life of this patent
Estimating the term…
Abstract
Provided herein are anti-angiogenic monoclonal antibodies and antigen-binding antibody fragments that selectively and specifically bind to an epitope in both fibronectin and either fibrinogen or fibrin fragment E, compositions containing these antibodies and antibody fragments, and methods of using these antibodies and antibody fragments.
Claims20
-57. (canceled)
A method of inhibiting solid tumor growth in a subject, the method comprising
- identifying a subject having a solid tumor;
- and
- administering to the subject a composition comprising an effective amount of a monoclonal antibody or antigen-binding fragment thereof that binds to human fibronectin, and human fibrinogen, and human fibrin fragment E.
Dependencies are inferred from the claim text.