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US 2019/0241629 A1Published application
Recombinant proteins derived from genus limulus, and dna molecules encoding same
AssigneeSeikagaku Corporation
InventorsHikaru MIZUMURA, Yuki KOBAYASHI, Toshio ODA
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Abstract
Provided are all full-length recombinant proteins involved in the clotting mechanism of Limulus polyphemus, cDNAs encoding the same, and applications thereof. A recombinant protein containing the amino acid sequence represented by SEQ ID NO: 2 or 4, a recombinant protein containing the amino acid sequence represented by SEQ ID NO: 6, 8, 10, or 12, a recombinant protein containing the amino acid sequence represented by SEQ ID NO: 14, 16, 18, 20, or 22, variants thereof, cDNAs encoding the same, and utilization thereof.
Claims4
A recombinant protein which is any of the following:
- (A) a recombinant protein that contains the amino acid sequence represented by SEQ ID NO:
- 2 or 4;
- (B) a recombinant protein that contains an amino acid sequence having a 95% or more identity with the amino acid sequence represented by SEQ ID NO:
- 2 or 4, and has factor C activity;
- (C) a recombinant protein that is encoded by a DNA containing a base sequence having a 95% or more identity with the base sequence represented by SEQ ID NO:
- 1 or 3, and has factor C activity;
- and
- (D) a recombinant protein that is encoded by a DNA hybridizing to a DNA composed of a complementary sequence to the base sequence represented by SEQ ID NO:
- 1 or 3 under stringent conditions, and has factor C activity.
6 more elements
Dependencies are inferred from the claim text.