Novel mesitylene-cored amphiphiles and uses thereof
AssigneeIndustry-University Cooperation Foundation Hanyang Erica Campus
InventorsPil Seok CHAE, Kyung Ho CHO
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AssigneeIndustry-University Cooperation Foundation Hanyang Erica Campus
InventorsPil Seok CHAE, Kyung Ho CHO
Estimating the term…
The present invention relates to a mesitylene-cored amphiphile, a method of preparing the same and a method of extraction, solubilization, stabilization, crystallization or analysis of a membrane protein using the same. When a mesitylene-cored compound according to the present invention is used, membrane proteins can be stored in a stable conformation for a long time in an aqueous solution in comparison with conventional compounds, by which the membrane proteins are usable in both functional and structural analyses thereof. The functional and structural analyses of membrane proteins are one of the fields that are most spotlighted in current biology and chemistry. The present invention can be used to research on a protein structure closely related to new drug development.
A compound represented by the following Formula 1:
A method of preparing a compound represented by the following Formula 1, comprising the steps of:
A method of extraction, solubilization, stabilization, crystallization or analysis of a membrane protein, comprising treating a membrane protein with a compound represented by the following Formula 1 in an aqueous solution:
Dependencies are inferred from the claim text.