Therapeutic compounds and uses thereof

A compound of formula (I):

• or a salt thereof, wherein:
• R1 is C1-12alkyl, C2-12alkenyl, C2-12alkynyl, 3-12 membered carbocycle, and 3-12 membered heterocycle, wherein each C1-12alkyl, C2-12alkenyl, C2-12alkynyl, 3-12 membered carbocycle, and 3-12 membered heterocycle of R1 is optionally substituted with one or more groups Rd;
• R2 is —C(O)—N(Re)2, —S(O)—N(Re)2, —S(O)2—N(Re)2, —C(O)—Re, —C(O)—O—Re, —S(O)—Re, or —S(O)2—Re,
• X is absent, —C(═O)—, or C1-3alkyl;
• and Y is phenyl, a 9-membered bicyclic carbocycle, a 10-membered bicyclic carbocycle, a 9-membered bicyclic heterocycle, or a 10-membered bicyclic heterocycle, wherein Y is optionally substituted with Ra and wherein Y is further optionally substituted with one or more groups Rb;
• or wherein —X—Y taken together is selected from the group consisting of:
• each Ra is independently selected from the group consisting of a 5-membered carbocycle, a 6-membered carbocycle, a 5-membered heterocycle, and a 6-membered heterocycle, which a 5-membered carbocycle, 6-membered carbocycle, 5-membered heterocycle, and 6-membered heterocycle are optionally substituted with one or more groups Rc;
• each Rb is independently selected from the group consisting of halo, cyano, hydroxy, amino, C1-4alkyl, C2-4alkenyl, C2-4alkynyl, C2-6cycloalkyl, (C2-6cycloalkyl) C1-4alkyl, C1-4alkoxy, C1-4alkoxycarbonyl, C1-4alkanoyl, —C(O)—N(Rf)2, —N(Rf)C(O)—Rf, and C1-4alkanoyloxy, wherein each C1-4alkyl, C2-4alkenyl, C2-4alkynyl, C2-6cycloalkyl, (C2-6cycloalkyl) C1-4alkyl, C1-4alkoxy, C1-4alkoxycarbonyl, C1-4alkanoyl, and C1-4alkanoyloxy, is optionally substituted with one or more groups independently selected from oxo, halo, amino, hydroxy, C1-3alkoxy, and C1-C3 alkyl that is optionally substituted with one or more groups independently selected from halo;
• each Rc is independently selected from the group consisting of halo, cyano, hydroxy, amino, C1-4alkyl, C2-4alkenyl, C2-4alkynyl, C2-6cycloalkyl, (C2-6cycloalkyl) C1-4alkyl, C1-4alkoxy, C1-4alkoxycarbonyl, C1-4alkanoyl, and C1-4alkanoyloxy, wherein each C1-4alkyl, C2-4alkenyl, C2-4alkynyl, C2-6cycloalkyl, (C2-6cycloalkyl) C1-4alkyl, C1-4alkoxy, C1-4alkoxycarbonyl, C1-4alkanoyl, and C1-4alkanoyloxy, is optionally substituted with one or more groups independently selected from oxo, halo, amino, hydroxy, C1-3alkoxy, and C1-C3 alkyl that is optionally substituted with one or more groups independently selected from halo;
• each Rd is independently selected from the group consisting of oxo, halo, cyano, hydroxy, amino, C1-4alkyl, C2-4alkenyl, C2-4alkynyl, C2-6cycloalkyl, (C2-6cycloalkyl) C1-4alkyl, C1-4alkoxy, C1-4alkoxycarbonyl, C1-4alkanoyl, and C1-4alkanoyloxy, wherein each C1-4alkyl, C2-4alkenyl, C2-4alkynyl, C2-6cycloalkyl, (C2-6cycloalkyl) C1-4alkyl, C1-4alkoxy, C1-4alkoxycarbonyl, C1-4alkanoyl, and C1-4alkanoyloxy, is optionally substituted with one or more groups independently selected from oxo, halo, amino, hydroxy, C1-3alkoxy, and C1-C3 alkyl that is optionally substituted with one or more groups independently selected from halo;
• each Re is independently selected from hydrogen, C1-4alkyl, C2-4alkenyl, C2-4alkynyl, and C2-5cycloalkyl, wherein each C1-4alkyl, C2-4alkenyl, C2-4alkynyl, and C2-5cycloalkyl is optionally substituted with one or more groups independently selected from oxo, halo, amino, hydroxyl, C1-3alkoxy, and C1-C3 alkyl that is optionally substituted with one or more groups independently selected from halo;
• and
• each Rf is independently selected from hydrogen and C1-4alkyl;
• or a compound selected from the group consisting of:
• or a salt thereof.