Resveratrol esters
AssigneeCOLE Research & Design, Inc.
InventorsMahmoud A. ElSohly, Waseem Gul, Jeptha N. Cole
Life of this patent
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Abstract
A resveratrol ester has the following structure: R1, R2 and R3 are H or Each R4 is independently a carbon chain of 2 to 4 carbon atoms comprising a terminal carboxylic acid moiety, a carbon chain of 1 to 5 carbon atoms comprising an amine moiety, or R5 is a carbon chain of 3 or 4 carbon atoms having a terminal carboxylic acid moiety. At least one of R1, R2 and R3 is Salts of resveratrol esters are also included.
Claims24
A resveratrol ester having the following structure:
- wherein R1, R2 and R3 are H or
- each R4 is independently a carbon chain of 2 to 4 carbon atoms comprising a terminal carboxylic acid moiety, a carbon chain of 1 to 5 carbon atoms comprising an amine moiety, —(CH2)3(NH)(R6), or
- R5 is a carbon chain of 3 or 4 carbon atoms having a terminal carboxylic acid moiety or a natural amino acid side chain,
- R6 is —(CO)(CH2)n(CO)(OH) and where n is 1 or 2, and
- at least one of R1, R2 and R3 is
- and salts thereof.
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A resveratrol ester selected from the group consisting of resveratrol hemimalonate, resveratrol hemisuccinate, resveratrol hemiglutarate, resveratrol 2-aminopropanoate, resveratrol 2-amino-3-methylbutanoate, resveratrol 2-amino-4-methylpentanoate, resveratrol 2-amino-3-methylpentanoate, resveratrol aminoethanoate, resveratrol 4-(4-aminophenyl)-butyrate, resveratrol 4-amino-butyrate, and resveratrol 6-amino-hexanoate.
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Dependencies are inferred from the claim text.