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US 2019/0240378 A1Published application
Low friction hydrogels and hydrogel-containing composite materials
AssigneeYeda Research and Development Co. Ltd.
InventorsJacob KLEIN, Ronit GOLDBERG, Noa IUSTER, Raya SORKIN
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Abstract
Hydrogels and composite material containing hydrogels and liposomes dispersed therein, which exhibit a reduced friction coefficient compared to neat hydrogels or composites containing hydrogels, processes for preparing the same, and methods for using the same are disclosed.
Claims20
A composition comprising a hydrogel or a composite material containing a hydrogel, and a plurality of liposomes dispersed throughout the bulk of said hydrogel, the composition being characterized by a shear storage modulus (G′) of at least 2000 Pa at a temperature of 25° C. and a frequency of 1 Hz,
- wherein:
- an average diameter of said liposomes is larger than 80 nm, said average diameter being a z-average determined by dynamic light scattering;
- and/or
- a degree of crosslinking of said hydrogel is higher than 0.2 molar percent, wherein said crosslinking comprises covalent crosslinking,
- and wherein a concentration of cholesterol in said liposomes is less than 40 molar percent relative to a total lipid amount of said liposome.
2 more elements
Dependencies are inferred from the claim text.