Use of Scavengers of Reactive Gamma-Ketoaldehydes to Extend Cell Lifespan and Healthspan
AssigneeVanderbilt University
InventorsL. Jackson Roberts, II, Thuy T. Nguyen
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Abstract
Methods and compounds for use in promoting survival of at least one eukaryotic cell, wherein the compounds are effective as gamma-ketoaldehyde scavengers.
Claims21
A method for promoting survival of at least one eukaryotic cell, comprising administering to said at least one cell an effective amount of at least one γ-KA scavenger compound, or a pharmaceutically acceptable salt thereof.
A method for treating or preventing a disease or disorder associated with cell death or aging in a subject, comprising administering to a patient in need thereof an effective amount of at least one γ-KA scavenger compound, or a pharmaceutically acceptable salt thereof.
A method for treating or preventing a neurodegenerative disorder in a subject, including Alzheimer's disease, comprising administering to a subject in need thereof a therapeutically effective amount of at least one γ-KA scavenger compound, or a pharmaceutically acceptable salt thereof.
21-40. (canceled)
Dependencies are inferred from the claim text.