# US 2019/0240165 A1 · Hair growth stimulating dressing

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- Number: US 2019/0240165 A1
- Document ID: US20190240165A1
- Status: Published application
- Kind: A1
- Application number: 15/886,837
- Filed: 2018-02-02
- Published: 2019-08-08
- Earliest claimed: 2018-02-02
- Assignees: National Taiwan Ocean University
- Applicants: National Taiwan Ocean University
- Inventors: HSIU-MEI LIN
- Web page: https://patentgrep.com/patent/US20190240165A1

## CPC

- A61K 9/703: {characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches}
- A61F 13/12: specially adapted for the head or neck
- A61K 8/0204: {Specific forms not provided for by any of groups A61K8/0208 - A61K8/14}
- A61K 8/0208: {Tissues; Wipes; Patches}
- A61K 8/0241: {Containing particulates characterized by their shape and/or structure (see also A61K8/04, A61K8/11, and A61K8/14, further aspects are classified in A61K2800/40 and subcodes)}
- A61K 8/19: containing inorganic ingredients
- A61K 8/25: Silicon; Compounds thereof
- A61K 33/244: Lanthanides; Compounds thereof (medicinal preparations containing radioactive lanthanides for use in therapy or testing in vivo A61K51/00)
- A61Q 7/00: Preparations for affecting hair growth
- A61K 2800/413: Nanosized, i.e. having sizes below 100 nm
- A61K: PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES (devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms A61J3/00; chemical aspects of, or use of materials for deodorisation of air, for disinfection or sterilisation, or for bandages, dressings, absorbent pads or surgical articles A61L; soap compositions C11D)
- A61F: FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS (dental prosthetics A61C)
- A61Q: SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS

## Abstract

The present invention discloses a hair growth stimulating dressing having advantages of simple manufacturing processes, low manufacture cost and reasonable selling price. To fabricate the hair growth stimulating dressing, it is firstly took mesoporous silica nanoparticles doped with lanthanide elements and at least one polymer matrix as raw materials to fabricate a plurality of biological fibers; and subsequently, the biological fibers are weaved to a biological textile. Particularly, the hair growth stimulating dressing can indeed show a promotion effect of hair growth on the heads of BALB/c nude mice after being covered onto the head of the nude mice. Therefore, compared to the fact that the commercial hair growth promoting products only just can show apparent hair growing effect on user's head after being continuously used for at least 4 months, this hair growth stimulating dressing only takes 7 days to exhibit positive hair growing effect on user's head.

## Claims

### Claim 1

A hair growth stimulating dressing, comprising a biological textile weaved by a plurality of biological fibers, wherein each of the plurality of biological fibers comprises:
a polymer sheath; and
a plurality of mesoporous silica nanoparticles doped with lanthanide elements, being doped in or enclosed by the polymer sheath.

### Claim 2 (depends on 1)

The hair growth stimulating dressing of claim 1, further comprising:
a substrate for supporting the biological textile; and
an adhesive layer, being formed on the biological textile.

### Claim 3 (depends on 1)

The hair growth stimulating dressing of claim 1, wherein the manufacturing material of the polymer sheath is selected from the group consisting of compound of gelatin and trifluoroethanol (TFE), compound of gelatin, TFE and polycaprolactone (PCL), compound of gelatin, TFE and polylactide (PLA), polyester, polyurethane (PU), polyvinyl chloride (PVC), polypropylene (PP), and polyamide (PA).

### Claim 4 (depends on 2)

The hair growth stimulating dressing of claim 2, wherein the substrate is provided with a glue layer thereon.

### Claim 5 (depends on 2)

The hair growth stimulating dressing of claim 2, wherein there are a plurality of air holes formed on the substrate.

### Claim 6

A hair growth stimulating dressing, comprising a biological textile weaved by a plurality of biological fibers and a plurality of fibers, wherein each of the plurality of biological fibers comprises:
a polymer sheath; and
a plurality of mesoporous silica nanoparticles doped with lanthanide elements, being doped in or enclosed by the polymer sheath.

### Claim 7 (depends on 6)

The hair growth stimulating dressing of claim 6, further comprising:
a substrate for supporting the biological textile; and
an adhesive layer, being formed on the biological textile.

### Claim 8 (depends on 6)

The hair growth stimulating dressing of claim 6, wherein the manufacturing material of the polymer sheath is selected from the group consisting of compound of gelatin and trifluoroethanol (TFE), compound of gelatin, TFE and polycaprolactone (PCL), compound of gelatin, TFE and polylactide (PLA), polyester, polyurethane (PU), polyvinyl chloride (PVC), polypropylene (PP), and polyamide (PA).

### Claim 9 (depends on 6)

The hair growth stimulating dressing of claim 6, wherein the manufacturing material of the sheath is selected from the group consisting of compound of gelatin and trifluoroethanol (TFE), compound of gelatin, TFE and polycaprolactone (PCL), compound of gelatin, TFE and polylactide (PLA), polyester, polyurethane (PU), polyvinyl chloride (PVC), polypropylene (PP), and polyamide (PA).
