Liquid formulations of daptomycin
AssigneeXellia Pharmaceuticals Aps
InventorsTina GJONI, Dubravka STRAZIC
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Abstract
The present invention relates to liquid pharmaceutical compositions comprising daptomycin, methods of providing such compositions and the use thereof. Provided herein are formulations comprising daptomycin, one or more polar protic solvents, and mixtures thereof. Formulations according to the present invention can further comprise polar aprotic solvent and/or source of calcium.
Claims18
A pharmaceutical formulation comprising
- daptomycin,
- one or more polar protic solvents, and
- an additional component selected from a polar aprotic solvent, a solubilizer, and a combination thereof.
A process for preparing pharmaceutical formulation of daptomycin comprising mixing daptomycin one or more polar protic solvents, and an additional component selected from a polar aprotic solvent, a solubilizer, or a combination thereof.
A method of treating an infection caused by Gram-positive pathogens.
Dependencies are inferred from the claim text.