Method for predicting severity and prognosis of cardiovascular disease
AssigneesNational University Corporation Nagoya University, Sysmex Corporation
InventorsRyosuke KIKUCHI, Kazuhiro Harada, Yohei Shibata, Hideki Ishii, Toyoaki Murohara
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Abstract
Disclosed is a method comprising acquiring a value relating to VEGF-A of a subject, wherein the value is a measured value of total VEGF-A in a blood sample, or a value obtained by dividing a measured value of VEGF-A165b in the blood sample by a measured value of total VEGF-A in the blood sample (VEGF-A165b/total VEGF-A), and the value suggests prognosis of myocardial infarction of the subject or severity of coronary artery disease of the subject.
Claims20
A method comprising acquiring a value relating to VEGF-A of a subject, wherein
- the value is a measured value of total VEGF-A in a blood sample, or a value obtained by dividing a measured value of VEGF-A165b in the blood sample by a measured value of total VEGF-A in the blood sample (VEGF-A165b/total VEGF-A), and
- the value suggests prognosis of myocardial infarction of the subject or severity of coronary artery disease of the subject.
A method for acquiring a value relating to VEGF-A of a subject, comprising:
- measuring total VEGF-A and VEGF-A165b in a blood sample obtained from the subject;
- calculating VEGF-A165b/total VEGF-A by dividing a measured value of VEGF-A165b in the blood sample by a measured value of total VEGF-A in the blood sample,
- wherein the value suggests prognosis of myocardial infarction of the subject or severity of coronary artery disease of the subject,
- the subject is a subject after the onset of myocardial infarction,
- it is suggested that the prognosis of myocardial infarction of the subject is poor when the VEGF-A165b/total VEGF-A is higher than a corresponding reference value,
- it is suggested that the prognosis of myocardial infarction of the subject is good when the VEGF-A165b/total VEGF-A is lower than the corresponding reference value.
A method for acquiring a value relating to VEGF-A of a subject, comprising:
- measuring total VEGF-A in a blood sample obtained from the subject,
- wherein the value suggests prognosis of myocardial infarction of the subject or severity of coronary artery disease of the subject,
- the subject is a subject after the onset of myocardial infarction,
- it is suggested that the prognosis of myocardial infarction of the subject is poor when the total VEGF-A measured value is lower than a corresponding reference value,
- it is suggested that the prognosis of myocardial infarction of the subject is good when the total VEGF-A measured value is higher than the corresponding reference value.
Dependencies are inferred from the claim text.