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US 2019/0195899 A1Published application
Particle-based drug detection method and device embodiments
AssigneeWashington State University
InventorsHerbert H. Hill, Jr., Brian Clowers, Nicholas Lovrich
Life of this patent
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Abstract
Disclosed herein are embodiments of methods for detecting the presence of and amount of drugs in a sample, particularly a particle sample obtained from a subject. In particular disclosed embodiments, the particle samples are skin particle samples, saliva particle samples, and/or mucous samples isolated from a subject and analyzed using thermal desorption methods combined with a selected detection method.
Claims26
A device, comprising:
- a particle-trapping component comprising a collecting medium configured to trap a sample introduced into the device;
- and
- a heat source configured to expose the sample introduced into the device to a temperature ranging from 100° C. to 500° C.;
- wherein the heat source is detachably coupled to the particle-trapping component.
1 more element
A device, comprising:
- a detachable sample conduit;
- a particle-trapping component detachably coupled to the detachable sample conduit;
- a body configured to receive the particle-trapping component, wherein the body is detachably coupled to the detachable sample conduit;
- a collecting medium disposed within the particle-trapping component, wherein the collecting medium is configured to trap a sample introduced into the sample conduit;
- and
- a heat source detachably coupled to the particle-trapping component, wherein the heat source is configured to expose the sample to a temperature ranging from 100° C. to 500° C.
3 more elements
A method, comprising:
- exposing a particle sample obtained from a subject to heat using thermal desorption to produce a volatilized sample from a solid component of the particle sample, wherein the solid component is a skin particle and/or a hair particle;
- and
- analyzing the volatilized sample to determine the presence of Δ9-tetrahydrocannabinol (THC) and/or other semi-volatile drugs absorbed onto the solid component of the particle sample prior to thermal desorption using spectrometry detection techniques, visual detection techniques, chromatography detection techniques, or combinations thereof.
Dependencies are inferred from the claim text.