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US 2019/0195860 A1Published application
Treatment of Neurodegeneration and Neuroinflammation
AssigneeBiogen MA Inc.
InventorMatvey Lukashev
Life of this patent
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Abstract
Methods of treating a subject having a condition characterized by at least one of neurodegeneration and neuroin-flammation are provided. Methods of reducing astrogliosis in a subject having a condition characterized by increased astrogliosis are also provided. Methods of providing neuroprotection to a subject in need thereof are also provided.
Claims13
1-40. (canceled)
A method of treating a subject having Friedreich ataxia, the method comprising administering to the subject a therapeutically effective amount of at least one compound of Formula I:
- wherein R1 and R2 are independently selected from OH, O−, and (C1-6)alkoxy, provided that at least one of R1 and R2 is (C1-6)alkoxy, or a pharmaceutically acceptable salt thereof.
Dependencies are inferred from the claim text.