Microfluidic chip device for optical force measurements and cell imaging using microfluidic chip configuration and dynamics

An apparatus for holding a microfluidic chip comprising:

• a cavity to hold the microfluidic chip;
• an integrated light source holder to allow for focused illumination in constrained space requirements;
• an integrated prism holder to allow a prism to reflect light to a desired location in or on the chip;
• threaded screw holes for screws to hold and allow for adjustment of the microfluidic chip;
• and
• threaded or non-threaded pass through holes for tubing and connector(s).

A device for moving cells and/or particles in fluid comprising:

• a substrate with multiple interior fluidic channels comprising:
• a first channel of the multiple interior channels disposed in the substrate in a manner such that a first plane oriented vertically with respect to the substrate traverses the first channel along its length;
• an opening disposed at an outer surface of the substrate and in operable communication with the first channel in a manner such that one or more substance is capable of entering and moving in the first channel vertically;
• a second channel of the multiple interior channels disposed in the substrate and in operable communication with the first channel in a manner such that a second plane oriented horizontally with respect to the substrate traverses the second channel along its length.