RAPID AND SIMPLIFIED DEVELOPING ANTIBODIES AND FABs OR OTHER MOLECULES CONSISTING OF AMINO ACIDS RECOGNIZING NATURAL ANTIGENS OR NON-NATURAL MOLECULAR TARGETS USING SPECIAL BLOCKING AGENT

A rapid and simplified method of developing antibodies or other monoclonal antigen-recognizing polypeptides, comprising:

• amino acids comprising polypeptides capable of recognizing and forming complexes with targeted antigens, comprised of natural or artificial molecular targets, using a Bioparticle Display Library approach, with each bioparticle of the Bioparticle Display Library containing genes composed of nucleic acids and capable of multiplying in the presence of a multiplication limiting factor;
• a polypeptide-carrying bioparticle identified and separated from a complex mixture of similar bioparticles of the Bioparticle Display Library using a first blocking agent, said first blocking agent consisting of a bioparticle, carrying only one individual type of polypeptide or not carrying any type of polypeptide, and resistant to different ones of the Bioparticle Display Library antibiotic or some other multiplication-limiting factor, or lacks resistance to any antibiotic, or to other multiplication-limiting agents;
• and
• performing only a single round of panning, multiplication, and screening using the blocking polypeptide-carrying bioparticle to generate a visible indicator of a desired biologic property.