Coryneform bacterial transformant and method for producing 4-aminobenzoic acid or salt thereof using same
AssigneesResearch Institute of Innovative Technology for the Earth, Sumitomo Bakelite Co., Ltd.
InventorsMasayuki INUI, Kazumi HIRAGA, Masako SUDA, Takeshi KUBOTA
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Abstract
Provided is a microorganism that is capable of efficiently producing para-aminobenzoic acid (4-ABA) or a salt thereof, using saccharides as raw materials, and a method for efficiently producing 4-ABA or a salt thereof by using this microorganism. A transformant obtained by introducing, into a coryneform bacterium, a gene that encodes 4-amino-4-deoxychorismate lyase, a gene that encodes a para-aminobenzoate synthase component I, and a gene that encodes a para-aminobenzoate synthase component II, is capable of efficiently producing 4-ABA or a salt thereof from saccharides.
Claims21
A transformant having 4 aminobenzoic acid producing ability, the transformant being obtained by introducing a gene that encodes an enzyme having para-aminobenzoate synthase component I activity, into a coryneform bacterium as a host.
A Corynebacterium glutamicum transformant ANI198 (NITE BP-02188).
Dependencies are inferred from the claim text.