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AssigneesKyowa Hakko Bio Co., Ltd., Kyowa Hakko Kirin Co., Ltd.
InventorsKana YAMAGUCHI, Shinichiro SHOJI, Masayoshi TSUKAHARA
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An object of the present invention is to provide a technique for stably, inexpensively, and safely culturing stem cells having a differentiation ability while maintaining an undifferentiated state. The present invention relates to a medium for culturing stem cells, comprising at least one or more compounds selected from the group consisting of a ROCK inhibitor, a PKC inhibitor, a histone methyltransferase inhibitor, and a retinoic acid receptor agonist, and not containing a growth factor or having a low growth factor concentration; a method for culturing stem cells using the medium; a growth promoter for stem cell; as well as a cell composition containing stem cells or differentiated cells therefrom; and a method for producing the cell composition.
A medium for culturing stem cells, comprising at least one or more compounds selected from the group consisting of a ROCK (Rho-associated coiled-coil forming kinase) inhibitor, a PKC (protein kinase C) inhibitor, a histone methyltransferase inhibitor, and a retinoic acid receptor agonist and not containing a growth factor or having a low growth factor concentration.
A growth promoter for stem cells, comprising at least one or more compounds selected from the group consisting of a ROCK inhibitor, a PKC inhibitor, a histone methyltransferase inhibitor, and a retinoic acid receptor agonist.
Dependencies are inferred from the claim text.