Support for culturing cells, method of preparing support, and method of culturing cells
AssigneeCha University Industry-Academic Cooperation Foundation
InventorsSurin HONG, Yong Soo CHOI
Life of this patent
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Abstract
Provided are a support for culturing cells, a method of preparing the support, and a method of culturing cells using the support. When the support and the methods are used, an adherence rate, a surface area, and a proliferation rate of cells may improve, and detachment of the cells may be facilitated, thereby increasing a cell recovery rate. In addition, a physiologically active substance may be slowly released, thereby reducing the cost for a cell culture process.
Claims16
A support for culturing cells, the support comprising:
- silica nanoparticles each having an open stoma, wherein physiologically active substance is comprised in an inner portion of the open stoma;
- and
- a solid support to which the silica nanoparticles are bound.
A method of preparing a support for culturing cells, the method comprising:
- performing, in a pressure vessel, hydrothermal treatment on a solution comprising a silica precursor, a polar solvent, a nonpolar solvent, an ionic surfactant, and a basic compound to prepare silica nanoparticles;
- incubating the silica nanoparticles and a physiologically active substance for binding the physiologically active substance to an inner portion of an open stoma of each of the silica nanoparticles;
- and
- binding, to a solid support, the silica nanoparticles to which the physiologically active substance is bound.
Dependencies are inferred from the claim text.