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US 2019/0194401 A1Published application
Composition with polymer and ceramic and methods of use thereof
AssigneeWake Forest University Health Sciences
InventorCarlos Kengla
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Abstract
Provided herein are improved compositions and methods of making and using the same, the composition comprising a polymer and a ceramic present at a ratio of from 3:1 to 1:3 of polymer:ceramic by weight, wherein the composition comprises or is a composite of the polymer and the ceramic having improved printability and/or having an improved elastic modulus and/or improved stress at failure (e.g., as compared to a blend of the polymer and the ceramic).
Claims22
A composition comprising:
- a biocompatible polymer;
- and
- a biocompatible ceramic.
- wherein said biocompatible polymer and said biocompatible ceramic are present in said composition at a ratio of from 3:1 to 1:3 of biocompatible polymer:biocompatible ceramic by weight, and
- wherein said composition comprises a composite of said biocompatible polymer and said biocompatible ceramic, said composite having improved printability and/or having an improved elastic modulus and/or improved stress at failure, as compared to a blend of said biocompatible polymer and said biocompatible ceramic.
2 more elements
A medical implant composition comprising:
- a biocompatible polymer;
- and
- a biocompatible ceramic,
- wherein said biocompatible polymer and said biocompatible ceramic are present in said composition at a ratio of from 3:1 to 1:3 of biocompatible polymer:biocompatible ceramic by weight, and
- wherein said composition comprises a composite of said biocompatible polymer and said biocompatible ceramic, said composite having improved printability and/or having an improved elastic modulus and/or improved stress at failure, as compared to a blend of said biocompatible polymer and said biocompatible ceramic.
2 more elements
A method of making a composition, said composition comprising:
- a biocompatible polymer;
- and
- a biocompatible ceramic,
- wherein said biocompatible polymer and said biocompatible ceramic are present in said composition at a ratio of from 3:1 to 1:3 of biocompatible polymer:biocompatible ceramic by weight,
- said method comprising:
- providing an organic solvent with the biocompatible polymer dissolved therein,
- adding the biocompatible ceramic to the organic solvent, wherein the biocompatible ceramic has an average particle size of about 100 nanometers, and wherein the organic solvent is at a temperature of 20-60° C., to form a mixture of the biocompatible polymer and the biocompatible ceramic,
- sonicating the mixture of the biocompatible polymer and the biocompatible ceramic at a frequency of 15-30 kHz, to form a sonicated mixture, and
- drying the sonicated mixture to form said composition.
6 more elements
Dependencies are inferred from the claim text.