US 2019/0194313 A1 · ANTIBODY OR AN ANTIGEN-BINDING FRAGMENT THEREOF CAPABLE OF BINDING TO A HUMAN RECEPTOR OF INTERLEUKIN-6

Antibody or an antigen-binding fragment thereof capable of binding to a human receptor of interleukin-6

AssigneeJoint Stock Company “Biocad”

InventorsStanislav Rudolfovich EVDOKIMOV, Andrei Borisovich ULITIN, Valery Vladimirovich SOLOVYEV, Aleksei Aleksandrovich ALEKSANDROV, Yulia Sergeevna CHERNYKH, Timofey Aleksandrovich NEMANKIN, Anna Konstantinovna VLADIMIROVA, Oleg Igorevich SMOTROV, Tatiana Veniaminovna CHERNOVSKAYA, Aleksandr Aleksandrovich MOSHCHENKO, Viktoriia Evgenevna NALOBINA, Roman Alekseevich IVANOV, Dmitry Valentinovich MOROZOV

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Abstract

The invention relates to medicine. The problem addressed by the present invention consists in creating alternative antibodies or fragments thereof which are capable of specifically binding to a human receptor of interleukin-6 and which would be useful as drugs for treating or diagnosing diseases, or for relieving symptoms, mediated by interleukin-6.

Claims25

Dependent claims

An antibody or antigen-binding fragment thereof having the ability to bind to a human interleukin-6 receptor (IL-6) comprising an amino acid sequence that is at least 75% identical to SEQ ID NO:

Dependencies are inferred from the claim text.

Facts

Application

16/325,528Filed 3 Aug 2017

Priority

RU 201613372017 Aug 2016

Published

27 Jun 2019

Term ends

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Classification22 codes

C07K 16/248
Interleukins [IL]: il-6
A61K 9/0073
Pulmonary tract; Aromatherapy: sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
A61K 9/19
Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles: lyophilised , i.e.…
A61K 39/395
Medicinal preparations containing antigens or antibodies: antibodies ; Immunoglobulins; Immune serum, e.g. antilymphocytic serum